Polymorphisms of Matrix Metalloproteinases (MMP) in COPD
نویسندگان
چکیده
منابع مشابه
Role of matrix metalloproteinases (MMPs) and MMP inhibitors on intracranial aneurysms: a review article
Cerebrovascular disease is one of the leading causes of death in the world, and about one-fourth of cerebrovascular deaths are due to ruptured cerebral aneurysms (CA). Hence it is important to find a way to reduce aneurysm formation and its subsequent morbidity and mortality. Proteolytic activity capable of lysing gelatin has been shown to be increased in aneurysm tissue and expressio...
متن کاملEvaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment
Recently, matrix metalloproteinases (MMP), in particular the gelatinases MMP-2 and MMP-9, generally considered as tumor markers for clinical applications. A longitudinal 2-years follow-up survey was performed on dogs with cutaneous tumor. Serum samples were obtained from 22 dogs with different cutaneous tumors and 22 health dogs at the time of surgery and one month, three months and one year af...
متن کاملMatrix metalloproteinases (MMP-1, -8, -13) in chronic periapical lesions.
BACKGROUND/AIM Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive lesions. The aim of this study was to determinate the correlation between concentration of collagenases (MMP-1, -8, -13) in chronic periapical le...
متن کاملExpression of Matrix Metalloproteinases (MMP-3 and MMP-9) in Skin Lesions of Leprosy Patients
Background. Leprosy is a chronic granulomatous disease, caused by Mycobacterium leprae (M. leprae), principally affecting peripheral nerves and skin. To date, the role of matrix metalloproteinases (MMPs) in different types of leprosy has not been studied, except for their role in neuropathy. Objective. to investigate the changes in expression and distribution of MMP-3 and MMP-9 in biopsies take...
متن کاملImmunohistochemical localisation of the matrix metalloproteinases MMP-3 and MMP-9 within the airways in asthma.
BACKGROUND The matrix metalloproteinase (MMP) enzymes MMP-3 and MMP-9 have relevance to the chronic structural airway changes in asthma. These proteinases can be generated by structural and inflammatory cells, and have the ability to degrade proteoglycans and thus potentially enhance airway fibrosis and smooth muscle proliferation through their ability to release and activate latent matrix boun...
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ژورنال
عنوان ژورنال: Biotechnology & Biotechnological Equipment
سال: 2012
ISSN: 1310-2818,1314-3530
DOI: 10.5504/50yrtimb.2011.0021